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Rushing this process, skipping dose levels, or starting at a higher dose to accelerate weight loss dramatically increases side effect severity

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470 One could argue that the success of sodium-glucose cotransporter 2 (SGLT2) inhibitors, and now of GLP-1RAs, suggests that metabolic abnormalities play an important role in driving HFpEF

This study revealed a pattern of postprandial hyperglycemia lasting 12 to 16 hours, suggesting that monitoring postprandial hyperglycemia after lunch or dinner is useful for diagnosing GIH [79]