15,16 Jennings et al 15 demonstrated a significant decrease in weight (6.5 kg), HS Physicians Global Assessment (HS-PGA) (from 4 to 1), DLQI (from 24 to 14), and analgesic use (from daily to not daily) but no decrease in CRP (from 3 mg/dL) after eight weeks of treatment
Kirson: Yeah, and I think also because if you think about it, the people who respond best to this medication, because there is something we didn't talk about, there's a subset of people who don't respond to these medications at all, you can put them on it and they just will not lose weight
Despite these interventions, a large proportion of patients have difficulties related to metabolic adaptation and/or maintaining D&E, which may contribute to the recovery of lost body weight [32]
Many of these sites offer prescriptions for GLP-1s after the user inputs some information including their weight without a virtual or in-person visit with a doctor