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Average Weight Loss on Semaglutide: What to Expect While weight loss varies from person to person (more on that below!), clinical studies show that Semaglutide can help patients lose 1 to 2 pounds per week which adds up to: 4 to 8 pounds per month 15% or more of your starting weight over several months Some patients may experience faster or slower results depending on their starting weight, lifestyle habits, and how their body responds to the medication
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