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Tirzepatide generally produces greater average weight loss in clinical studies, while semaglutide has a longer history of use and remains a popular option for many patients

Drug interactions : Tirzepatide and some short-acting GLP-1 receptor agonists may delay absorption of oral medications due to gastric emptying effects

Had you waited through the transition (usually one to two weeks), the spike would have resolved and you would have settled into a comfortable steady state at 7.5 mg