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Hence, by targeting the enzymatic activity of SARM1, inhibitors may effectively prevent the depletion of NAD + , thereby maintaining cellular energy homeostasis and enhancing neuronal resilience, potentially expanding the treatment landscape for various neurological conditions

Ferroptosis deficiency attenuated TGF--induced fibrosis in HK-2 cells via GPX4 overexpression These results demonstrated that ferroptosis inhibition improved fibrotic changes in vitro and in vivo

CrossRef Extracellular RNAs in Liquid Biopsy: Applications in MASLD and MASH Diagnosis and Monitoring Dimitrios Raptis, Shiny Teja Kolli, Sonal Agarwal, Praveen Kumar Komminni, Prashamsha Bhattarai, Prinka Hablani, Rahul Kumar, Petras Das, Martin McIntosh, Michail Kladas, Priyanka Gokulnath, Michail Spanos Diagnostics .2025