470 In this study, researchers randomized 529 patients with heart failure with a preserved ejection fraction and body mass index (weight in kilograms in the square of the height in meters) 30 to receive once-weekly injections of semaglutide (2.4 mg) or placebo for 52 weeks
PMC2342623 Kandalla PK, Goldspink G, Butler-Browne G, Mouly V (2011) Mechano Growth Factor E peptide (MGF-E), derived from an isoform of IGF-1, activates human muscle progenitor cells and induces an increase in their fusion potential at different ages
ASC37 is a GLP-1/GIP/glucagon triple agonist the same receptor profile as Lilly's retatrutide
Exogenous pigmentation from medication results when the drug metabolite becomes deposited in the oral hard or soft tissue
In June 2025, MBX Biosciences announced that it has submitted an IND application to the FDA for MBX 4291, a long-acting GLP-1/GIP receptor co-agonist prodrug targeting obesity, which received regulatory clearance in July