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Repeated freezethaw cycles should be avoided, as they may compromise peptide structure

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As the confounding structure for the head-to-head comparison of tirzepatide versus semaglutide was expected to be more similar to the tirzepatide versus dulaglutide benchmarking study, we proceeded with the prespecified analysis plan that included death in the primary composite MACE outcome

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Protection Against Encephalitis : The drug showed a significant reduction in the risk of encephalitis, a life-threatening inflammation of the brain 1