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Under intestinal inflammation, increased intestinal permeability allowed for bacterial translocation and passage from the portal vein into the liver, contributing to the pathogenesis of numerous diseases such as AIH and cholestatic liver disease

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In addition to directly influencing satiety and appetite control via hypothalamic and hindbrain pathways, GLP-1RAs appear to engage higher-order networks involved in reward processing and emotional regulation, such as the insula, amygdala, and medial prefrontal cortex

Portion control is paramounteven with healthy snacks like popcorn

2025 [cited 2025 Apr 25]