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Alvarez-Sala A, Lpez-Garca G, Attanzio A, Tesoriere L, Cilla A, Barber R, et al

You chew it slowly for 10 to 15 minutes to allow absorption through the oral tissue

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Its a combination of all three of these factors. Since the study was retrospective, it is not enough to change practice, so large randomized clinical trials addressing this question are needed, Sheth said