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Freeman has been providing MAXONA with key scientific, medical, and clinical development guidance since the company's inception and is the founder and current Chairman of its Scientific Advisory Board (SAB)
When mitophagy is dysregulated, damaged mitochondria accumulate, resulting in mitochondrial DNA damage, ROS amplification, energetic collapse, and cardiomyocyte death
Like other plant butters, Cacao seed butter is an emollient
Modified from Ravassa et al
Administration of spironolactone, a selective MR antagonist, counteracted stress-induced mGlu2 suppression and the related development of depressive-like behavior, implicating rapid action of glucocorticoids via a receptor that is known to modulate glutamate release [20]
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