In the STEP 3 randomised trial, once weekly semaglutide 2.4 mg used in obese adults without diabetes was associated with 4.9% incidence of gallbladder related disorders (mainly cholelithiasis) compared with 1.5% in the placebo group (1)
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Sanyal, Ant Nature Medicine .2026;[Epub] CrossRef Bisphenol S induces hepatic steatosis and insulin resistance through AMPK inhibition and endoplasmic reticulum stress Vinicius Seplveda-Fragoso, Emanuelle Barreto-Reis, Thais de Souza Carvalho-Laureano, Milena Barcza Stockler-Pinto, Eliete Dalla Corte Frantz, Denise Pires de Carvalho, Xavier Palomer, Emma Barroso, Manuel Vzquez-Carrera, Leandro Miranda-Alves, D'Angelo Food and Chemical Toxicology .2026
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