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Human presenilin-1, but not familial Alzheimers disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing
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Why it matters: Fiber is critical for gut health, regular bowel movements, and feeling satisfied
Similarly, thromboembolic events and cardiovascular toxicity may reflect the combined effects of erythrocytosis, dehydration induced by diuretics, stimulant-related vasoconstriction, and adverse lipid alterations (92, 95)
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