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A body mass index (BMI) of 30 or more characterizes obesity in adults, whereas a BMI over 40 characterizes severe obesity

If cognitive symptoms are severe or persistent despite intervention, alternative weight management strategies may be considered in accordance with NICE guidance

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However, triple receptor agonism, or agonism/antagonism combinations, can be achieved not only though unimolecular triple agonists, but also by combining mono- and dual-agonists

E., Tajiri, N., Kaneko, Y., & Freeman, T