Waist shrinks while scale weight stays flat the most common surprise
A limitation of the current trials is that translation to clinical practice should be made with caution, as is always the case for results obtained in an experimental setting
In addition, biological outcomes (such as alanine aminotransferase [ALT], aspartate aminotransferase [AST], hemoglobin A1c [HbA1c], fasting plasma glucose [FPG], homeostasis model assessment of insulin resistance [HOMA-IR], total cholesterol [T-Chol], low-density lipoprotein-cholesterol [LDL-C], and triglycerides [TG]) and anthropometric outcomes (such as body mass index [BMI] and waist circumference [WC]) were analyzed for further comparison
Effect sizes for drinking outcomes were medium to large, similar to whats been seen with injectable semaglutide
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