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But personalized obesity care in the future might GLP-1s don't always work for weight loss

Tirzepatide is a dual agonist: it acts on both of the gut-hormone receptors that signal fullness, rather than GLP-1 alone

[14] [15] Heart rate changes: GLP-1 receptor agonists are associated with a modest increase in resting heart rate

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The TRIUMPH clinical trial program includes multiple Phase 3 studies spanning weight loss , type 2 diabetes, metabolic conditions , liver disease, and even knee osteoarthritis