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Effect of an intensified multifactorial intervention on cardiovascular outcomes and mortality in type 2 diabetes (J-DOIT3): an open-label, randomised controlled trial
Methylation pathways become saturated, and excess methionine is converted to homocysteine, which may contribute to cardiovascular risk if B-vitamin cofactors (B6, B12, folate) aren't adequate
Benefits include: \Tissue Regeneration: May help speed up recovery of muscles, tendons, and ligaments after injury (Animal Study)
A 2025 joint advisory from leading nutrition and obesity organizations emphasized nutrient-dense meals, GI side-effect management, and adequate protein intake as key priorities for people using GLP-1 medication