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Initially developed for Type 2 Diabetes (T2D), GLP-1 drugs are now widely used in obesity/weight loss management, with emerging applications in cardiovascular and neurodegenerative diseases

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The activities of DHAR and GR were also found to be increased under heat stress in temperature sensitive orchid Phalaenopsis (Ali et al., Similar to heat stress, low temperature stress also induces H 2 O 2 production in cells (Suzuki and Mittler, 2006) and is known to up-regulate transcripts, protein level and activities of different ROS-scavenging enzymes (Prasad et al., 1995

Statistical analysis Yearly prevalence and incidence were calculated as the number of prevalent and incident patients dispensed a GLP-1 RA, at least once during the year, divided by the Regions yearly population [40]