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The Aib residue at position 2 and the fatty acid modification both confer resistance to the primary degradation enzymes (DPP-4 and neprilysin), extending the metabolic half-life

This is crucial for maintaining continuity of care as patients move between providers

Separately, research shows the peptide promotes growth hormone receptor expression in fibroblasts and myosatellite cells, supporting collagen synthesis and tissue remodeling at wound sites