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volume depletion risk via natriuresis | Lithium toxicity if dehydrated | Moderate | Monitor serum lithium
GLP-1(2836) binds MTP
Shelf Life: 24 months
Int J Mol Sci 20(10):2407
Pros: Naturally occurring in the body, giving it a favorable long-term safety profile compared to many synthetic peptides Backed by decades of published research on collagen synthesis, wound healing, and antioxidant activity Available in both topical (cosmetic-legal) and injectable forms depending on desired intensity Cons: Injectable/research-grade product is not standardized or quality-controlled the way pharmaceuticals are, so purity varies significantly by vendor High topical concentrations can cause skin irritation, and there is limited long-term human trial data for injectable use Side Effects: Topical use is generally well tolerated, with occasional mild redness, tingling, or dryness at the application site
