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Because IV delivery achieves near-complete bioavailability by bypassing the digestive system entirely, the nutrient impact per session tends to be more comprehensive, which can extend the interval between treatments compared to single-nutrient injections

doi:10.3389/fncel.2015.00003 Uribe PM, Hudson AM, Lockard G, et al

The tissue surrounding the injection point, which maintains a tightly regulated pH environment, responds to this disruption with the brief inflammatory signals that produce the stinging or burning sensation

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The half-life of GHRP-2 is about 30 minutes and about 2-3 hours for GHRP-6