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While it has not been conclusively established whether this dysfunction is a cause or consequence of the pathological processes, growing evidence suggests that reduced proteasomal activity may contribute to the accumulation of toxic protein aggregates and the progression of neurodegeneration

May 15 2023;17(2):87-94

Metabolic syndrome is characterized by central obesity, insulin resistance, elevated blood pressure, high triglyceride, and low high-density lipoprotein levels 2