This is generally a positive sign of improved metabolic function but may require dietary awareness, particularly in patients managing their weight
Importantly, we have unraveled a key role of visceral WAT, not analyzed in-depth in previous studies, as an early target of our dualAG that triggers subsequent metabolic responses in the pancreas and liver, leading to BAT activation and WAT beiging
This includes people taking insulin or sulfonylureas, patients with diabetes, patients on blood pressure medications, patients with kidney disease or dehydration risk, patients with a gallbladder history, patients with significant reflux or gastroparesis symptoms, patients with eating disorder history, and patients who have difficulty meeting protein or fluid needs
(2023) Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes
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