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In addition, two subtypes of neutrophils have been reported at least in murine tumor models: TGF-independent type 1 (N1) with antimicrobial functions, and TGF-dependent tumor-associated neutrophils (N2, TANs) possessing pro-tumor and proangiogenic functions [263, 264]

During protein folding stress, the sirtuin SIRT7 also plays an important role by contributing to repressing nuclear respiratory factor 1 (NRF1) activity, a major transcriptional regulator of mitochondrial genes

Nitration of gamma-tocopherol prevents its oxidative metabolism by HepG2 cells

The 12-week study involved 80 male volunteers aged 18 to 50 with poor sperm quality

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