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Results showed that the ingredient significantly increased NAD+ levels in senescent fibroblasts, activated the SIRT1 signaling pathway, reduced the expression of senescence-associated -galactosidase (SA--gal), decreased intracellular reactive oxygen species accumulation, and promoted collagen synthesis

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KLOW Dosage and Frequency Chart The standard KLOW protocol uses a 3.2 mg dose, or a 10-unit draw from an 80 mg KLOW vial reconstituted with 2.5 mL BAC water