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Secondly, we did not have access to hepatic tissues in subjects, and cannot definitely rule out that there may be some dietary influence on flavin monooxygenasedependent conversion of TMA to TMAO
Currently there are no studies confirming safe or effective use in humans either taken orally or injected
It is well established that patients with diabetes demonstrate higher susceptibility to pancreatic cancer and pancreatitis compared to non-diabetic individuals, and theoretically, sustained GLP-1 receptor activation induced by GLP-1RA therapy may potentially elevate pancreatic cancer risk [8]
It should only be used by trained research professionals
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