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Regular monitoring of serum copper and ceruloplasmin levels may be warranted for long-term users, particularly those exceeding recommended dosages

Figure 1 3.3 Association between GLP-1RA exposure and opioid use disorder Exposure to any GLP-1 RAs was significantly associated with reduced odds of OUD diagnosis

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Semaglutide, a GLP-1 receptor agonist, mimics the natural incretin hormone GLP-1 to enhance insulin secretion, slow gastric emptying, and increase satiety