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The following results were seen after 12 weeks of treatment as compared with before treatment: people who took Vyvanse had, on average, 3.87 to 3.92 fewer binge days* per week people who took a placebo had, on average, 2.26 to 2.51 fewer binge days per week In another clinical trial, adults took Vyvanse for 12 weeks

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As we expected, either GLP-1R blockade or PKA inhibition partially eliminated the protective effects of the combined therapy on endothelial function