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These conditions include type 2 diabetes, high blood pressure, or high cholesterol
Among GLP-1based medications, tirzepatide is often considered one of the most potent options because it activates both GLP-1 and GIP receptors
Interestingly, the categories enriched in the upregulated clusters are related to phagosome maturation, RNA and translation, but importantly multiple metabolism pathways including citric acid cycle, cholesterol metabolism, pentose phosphate pathway, electron transport chain, and glutathione metabolism
Lower doses can sometimes reduce nausea, bloating, constipation, and other gastrointestinal side effects
Theranostics 12:72167236
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