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PMID: 32558293 | doi:10.1002/brb3.1726 Gwyer D et al
The most common causes include B12 supplementation (particularly injections), liver disease releasing stored B12, haematological disorders increasing B12-binding proteins, and chronic kidney disease reducing B12 excretion
The glucagon component adds something unique: reduced lipogenesis in the liver means the body is less efficient at converting dietary fat into stored fat, which alters the metabolic feedback loops that regulate hunger
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Improved Blood Sugar Control: GLP-1 can be particularly beneficial for individuals with obesity and type 2 diabetes, as it helps regulate blood sugar levels alongside promoting weight loss
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