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Obesity and meningioma: a US population-based study paired with analysis of a multi-institutional cohort

Therefore, a possible mechanism proposed by the authors is that the activation of the farnesoid X receptor (FXR) by exendin-4 stimulates the expression of FGF15 in the small intestine and inhibits the expression of cytochrome P450 family 7 subfamily A member 1 (Cyp7a1) in the liver through fibroblast growth factor receptor 4 (FGFR4), thereby reducing fecal bile acid excretion and liver bile acid synthesis [75]

They stimulate GH release through entirely different receptor pathways and can be combined for additive effect

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EFORT Open Reviews 7 (5), 295304