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[120] HC is present in saliva
It has demonstrated oral stability in gastric juice and efficacy even at microgram or nanogram doses
There are also certain drugs and health conditions that can increase the likelihood of developing a B12 deficiency such as: alcohol abuse, antacid use, smoking, celiac disease, other digestive concerns, pregnancy, a strict vegetarian or vegan diet, and even natural aging
A minimum of 8 weeks appears necessary to observe meaningful changes in chronic conditions, with 10 to 12 week cycles common
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