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Furthermore, GLP-1 RAs play a pivotal role in the alleviation of oxidative stress, the maintenance of mitochondrial homeostasis, and the inhibition of cell apoptosis and pyroptosis in models of ischemic cardiomyopathy [16]

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108 LC15-0444 (a DPP4inh) decreased inflammatory and fibrotic indicators like TGF1, toll-like receptor 4, HMGB1, NADPH oxidase 4, nuclear factor kappa B, and modified Smad2/3 in this TGF-driven model

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