Kai Uwe Lewandowski, Professor of Surgery at the University of Arizona School of Medicine, noted, Depression was the most commonly reported adverse event associated with these drugs, followed by anxiety and suicidal ideation
From a public health standpoint, the impact of TMAO elevation during l-carnitine supplementation is unknown, but both vegan/vegetarian and omnivore on average showed a greater than 10-M increase in circulating TMAO levels with l-carnitine supplementation
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For these patients, it is prescribed as a treatment for the reduction of excess abdominal fat and shown to decrease the visceral adipose tissue and waist circumference [2]