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Blocks the enzyme responsible for triggering melanogenesis in the skin

In some embodiments, the trans-epithelial administration provides an area under a curve (AUC TE ) of the therapeutic agent in systemic circulation versus time of about 10% to about 99%, for example, at least about 10%, at least about 15%, at least about 20%, at least about 25%, at least about 30%, at least about 35%, at least about 40%, at least about 45%, at least about 50%, at least about 55%, at least about 60%, at least about 65%, at least about 70%, at least about 75%, at least about 80%, at least about 85%, or at least about 90% as the AUC obtained when the same amount of the therapeutic agent is delivered subcutaneously (to the same subject, or to a population of subjects) (AUC SC )

Benefits: These carbs, when paired with fiber and protein, offer energy without causing large spikes in blood sugar

Common side effects of short-term prednisolone include increased appetite, mood changes, difficulty sleeping, and raised blood glucose particularly relevant for people with diabetes

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