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There is clear evidence for the use of B12 in diabetic neuropathy, either alone or with other treatments, and in lowering homocysteine levels, again either alone or with other nutrients

Storing a vial on its side or inverted keeps the solution in sustained contact with the rubber stopper, which pharmaceutical literature describes as a potential leachable-contamination pathway over extended periods

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People with insufficient B12 often experience an imbalance in energy production and nutrient use

After all, completely eliminating Methionine from a human diet would be nearly impossible (Methionine is found in meat, fish, and dairy)