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Abbreviations: AUC: area under the curve

Scirica BM, Bhatt DL, Braunwald E, Steg PG, Davidson J, Hirshberg B, Ohman P, Frederich R, Wiviott SD, Hoffman EB, Cavender MA, Udell JA, Desai NR, Mosenzon O, McGuire DK, Ray KK, Leiter LA, Raz I, Committee S-TS, and Investigators

The role of G protein-coupled receptor kinases in GLP-1R -arrestin recruitment and internalisation

Theyre not recommended if you have: Gastroparesis or severe GI conditions A personal or family history of medullary thyroid carcinoma or MEN2 genetic syndrome A history of pancreatitis Pregnancy or are breastfeeding Diabetic retinopathy (risk of worsening with rapid glucose drops) Always share your full health history with your providertransparency is critical for safe recommendations

Dose flexibility