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Mechanistically, FA reacts with the redox-active thiol group of glutathione (GSH), altering the GSH:GSSG ratio and causing oxidative stress
The deficiency of glutathione leads to increased levels of oxidative stress, which might further lead to chronic diseases such as cancer, diabetes, and rheumatoid arthritis
C-GSHf_Fwd 5-GGGCGGAATTTACGTAGCTTAAGT-3;C-GSHf_Rev List of other constructs in the manuscript PMXS_IRES_BLAST_Hu_SLC25A39
NPJ Vaccines 6:127
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