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Sci Rep 7(1):6224
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76 GST prodrugs appear to have a more favorable adverse-event profile, given that they are ingested as an inactive compound and undergo breakdown to release cytotoxic metabolites only in the presence of high concentrations of enzymes that occur in the proximity of tumor cells, thereby reducing collateral damage to healthy cells
Most published research uses in vitro adipocyte models and animal studies to assess whether AOD9604 modulates biochemical markers linked to lipolysis and lipogenesis
