Funding This work was supported by Japan Agency for Medical Research and Development (AMED) (23ama221520h0001 to K.S.), a Grant-in-Aid for Scientific Research (B) 20H03668, BRIDGE (programs for bridging the gap between R&D and the ideal society (Society 5.0 to RH and KS) and generating economic and social value to K.S.), the National Cancer Center Research and Development Fund (2022-A-20, 2023-J-2, NCC Biobank, and NCC Core Facility to K.S.), and the Yamagata Prefectural Government and City of Tsuruoka (HM)
In summary, current clinical data confirms that NAC is a safe adjunctive therapy with a minimal risk of severe adverse effects for chronic respiratory conditions
Some evidence suggests that individuals with impaired glucose tolerance may exhibit different GLP-1 responses to dietary stimuli compared to metabolically healthy individuals, though specific data regarding allulose in this context remain limited
Both telogen effluvium and unmasking of androgenic alopecia are possible
Reaching for high-hanging fruit in drug discovery at proteinprotein interfaces