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Studies have found that glutathione production decreases as people age, especially when women go through menopause
Kirkland RA, Franklin JL
Rather than new side effects, what people most often notice is a return of what the medication was managing
Thus signalling through ER is beneficial and ER detrimental to repair
It is important to note that this mechanism is a plausible hypothesis based on what is understood about GLP-1-based therapies more broadly
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