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Despite inherent limitations of observational data and potential for residual confounding, the results from these observational analyses support, in line with RCT findings, combining SGLT2is and GLP-1RAs to reduce cardiovascular events in patients with diabetes in routine clinical care [12, 23, 43, 63]

PLoS One 12 , e0178699 (2017)

Ten to twelve years is a relatively short period of time to study the long-term effects of a new class of drugs

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GLP-1 injections can have a similar impact for people who historically struggle to maintain a healthy relationship with food