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Activation of large-conductance (BK Ca ) and small-conductance (K Ca ) K + channels, as well as ATP-sensitive K + (K ATP ) channels, induces K + efflux, reducing Ca 2+ entry through voltage-gated calcium channels (VGCCs), leading to pericyte hyperpolarization and increased CBF [93]
Available sizes include 100 mg, 50 mg, subject to live stock
Without neurological symptoms, around 3 injections over 2 to 3 weeks is standard
Low dose, slow increase
If using clear vials, wrap them in aluminum foil
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