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[11] [12] When activated, these receptors trigger several beneficial effects: Enhanced insulin secretion in response to elevated blood glucose levels Suppression of glucagon release , reducing hepatic glucose production Delayed gastric emptying , which promotes satiety and reduces appetite Direct effects on appetite centres in the hypothalamus Commonly prescribed GLP-1 receptor agonists available in the UK include semaglutide (Ozempic, Wegovy, Rybelsus), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and exenatide (Byetta, Bydureon)
Here is what that looks like in practice: These are starting points, not hard rules
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Liver Protection vs Liver Stress: The Paradox One of the more interesting aspects of GLP-1 receptor agonists is their protective effect on the liver in certain contexts, particularly reducing fatty liver disease
Real-world protocols: putting it all together Protocol 1: beginner (just starting semaglutide) Weeks 1-4 (semaglutide 0.25mg): Focus on adjusting to semaglutide
