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Here, we establish methodology for calculating occupancy of each receptor for clinically efficacious doses of the drug
The results showed that, in five of the studies that could be pooled and analyzed together, chamomile significantly improved PSQI scores, reflecting better overall sleep quality
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The clinical data underscores both the potential and the challenge: while mechanistic studies are convincing and smaller trials encouraging, large randomized trials sometimes fail to meet endpoints, reminding us of patient complexity and the need to target the right patients
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