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As dopamine does not cross the digestive mucosa or the bloodbrain barrier, oral administration of its lipophilic precursor l-dopa remains pivotal as therapy 1

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Although gastric banding carries a lower risk of B12 deficiency than malabsorptive procedures such as Roux-en-Y bypass, reduced tolerance of B12-rich foods and the use of acid-suppressing medicines can still compromise nutritional status over time