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doi:10.1201/9781315119540
16 This statement recommended that sponsors demonstrate the safety of their products for patients with cardiovascular (CV) disease, as most phase II and III trials excluded such patients
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Cirrhosis is somewhat extreme (compared with simple steatosis) since, besides the liver disease, which disrupts the liveralpha cell axis, individuals with cirrhosis are at high risk of kidney disease, which is often associated with hyperglucagonaemia [104]
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