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Interestingly, hyperplasia of selected EEC subtypes in response to intestinal infection is probably dependent on immune cells, since serotonin (5-HT)-producing cell hyperplasia associated with Citrobacter rodentium infection was absent in mice lacking adaptive immunity ( + T cells were necessary to increase numbers of 5-HT producing enterochromaffin cells during helminth infection (149)

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It is stable to autoclaving for short periods at 121C