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FIGURE 6 Moreover, in vitro Western blotting further revealed a decrease in Nrf2 and HO-1 protein levels in HBZY-1 cells exposed to Gd-IgA1, with the subsequent reversal of these alterations upon Lut treatment (Figures 6D,E)

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Emerging evidence suggests that GLP-1 receptor agonists can suppress dopamine signaling in reward circuits, effectively lowering the volume on cravings ( PMC , 2024)