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Using it incorrectly can lead to serious problems

2.3 Selecting the literature (inclusion and exclusion criteria) Articles included in this scoping review met specified inclusion criteria: (i) cross-sectional studies, pre-clinical studies, randomized controlled trial design, systematic and umbrella reviews, grey literatures published from 2014 to 2024 and (ii) all age patient populations

84 Another study found higher intakes of folate and vitamin B12 were both associated with lower homocysteine levels and better sperm parameters in men with MTHFR polymorphisms

This patient has four simultaneous factors compromising b12 status, making supplementation prudent even with normal baseline levels

Therefore, use of contraception is recommended while taking this medicine