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Li Y, Perry T, Kindy MS, et al

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Moreover, GLP-1RAs may affect tumor initiation and progression by modulating microRNA expression patterns and influencing epigenetic modifications

Lastly, the results of a very recent systematic review and network meta-analysis aimed to compare the effects of oral antidiabetic drugs in endocrine and metabolic profiles in patients with PCOS confirmed that metformin was more beneficial in reducing serum total testosterone, whereas GLP-1RA + metformin reduced FAI more effectively [24]

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